diff --git a/compiler/driver/compiler_driver.cc b/compiler/driver/compiler_driver.cc
index 27cfe19..60537fd 100644
--- a/compiler/driver/compiler_driver.cc
+++ b/compiler/driver/compiler_driver.cc
@@ -384,6 +384,12 @@
     Thread* self, const CompilerDriver& driver, Handle<mirror::ClassLoader> class_loader,
     const DexFile& dex_file, const DexFile::ClassDef& class_def)
     REQUIRES_SHARED(Locks::mutator_lock_) {
+  // When the dex file is uncompressed in the APK, we do not generate a copy in the .vdex
+  // file. As a result, dex2oat will map the dex file read-only, and we only need to check
+  // that to know if we can do quickening.
+  if (dex_file.GetContainer() != nullptr && dex_file.GetContainer()->IsReadOnly()) {
+    return optimizer::DexToDexCompiler::CompilationLevel::kDontDexToDexCompile;
+  }
   auto* const runtime = Runtime::Current();
   DCHECK(driver.GetCompilerOptions().IsQuickeningCompilationEnabled());
   const char* descriptor = dex_file.GetClassDescriptor(class_def);
diff --git a/compiler/driver/compiler_driver.h b/compiler/driver/compiler_driver.h
index 773632c..b51e0de 100644
--- a/compiler/driver/compiler_driver.h
+++ b/compiler/driver/compiler_driver.h
@@ -107,13 +107,13 @@
 
   ~CompilerDriver();
 
-  // Set dex files that will be stored in the oat file after being compiled.
+  // Set dex files associated with the oat file being compiled.
   void SetDexFilesForOatFile(const std::vector<const DexFile*>& dex_files);
 
   // Set dex files classpath.
   void SetClasspathDexFiles(const std::vector<const DexFile*>& dex_files);
 
-  // Get dex file that will be stored in the oat file after being compiled.
+  // Get dex files associated with the the oat file being compiled.
   ArrayRef<const DexFile* const> GetDexFilesForOatFile() const {
     return ArrayRef<const DexFile* const>(dex_files_for_oat_file_);
   }
@@ -530,7 +530,7 @@
 
   bool support_boot_image_fixup_;
 
-  // List of dex files that will be stored in the oat file.
+  // List of dex files associates with the oat file.
   std::vector<const DexFile*> dex_files_for_oat_file_;
 
   CompiledMethodStorage compiled_method_storage_;