diff --git a/Lib/test/test_io.py b/Lib/test/test_io.py
index af3b90a..2a3b4a3 100644
--- a/Lib/test/test_io.py
+++ b/Lib/test/test_io.py
@@ -1474,6 +1474,12 @@
         pair = self.tp(SelectableIsAtty(True), SelectableIsAtty(True))
         self.assertTrue(pair.isatty())
 
+    def test_weakref_clearing(self):
+        brw = self.tp(self.MockRawIO(), self.MockRawIO())
+        ref = weakref.ref(brw)
+        brw = None
+        ref = None # Shouldn't segfault.
+
 class CBufferedRWPairTest(BufferedRWPairTest):
     tp = io.BufferedRWPair
 
diff --git a/Misc/NEWS b/Misc/NEWS
index 47de844..888abf5 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -29,6 +29,9 @@
 Library
 -------
 
+- Issue #22517: When a io.BufferedRWPair object is deallocated, clear its
+  weakrefs.
+
 - Issue #10510: distutils register and upload methods now use HTML standards
   compliant CRLF line endings.
 
diff --git a/Modules/_io/bufferedio.c b/Modules/_io/bufferedio.c
index 758edf4..62a350b 100644
--- a/Modules/_io/bufferedio.c
+++ b/Modules/_io/bufferedio.c
@@ -2120,6 +2120,8 @@
 bufferedrwpair_dealloc(rwpair *self)
 {
     _PyObject_GC_UNTRACK(self);
+    if (self->weakreflist != NULL)
+        PyObject_ClearWeakRefs((PyObject *)self);
     Py_CLEAR(self->reader);
     Py_CLEAR(self->writer);
     Py_CLEAR(self->dict);