diff --git a/Lib/_pyio.py b/Lib/_pyio.py
index 83bce70..87c833c 100644
--- a/Lib/_pyio.py
+++ b/Lib/_pyio.py
@@ -747,6 +747,10 @@
     def mode(self):
         return self.raw.mode
 
+    def __getstate__(self):
+        raise TypeError("can not serialize a '{0}' object"
+                        .format(self.__class__.__name__))
+
     def __repr__(self):
         clsname = self.__class__.__name__
         try:
diff --git a/Lib/test/test_io.py b/Lib/test/test_io.py
index 680e36d..91dd803 100644
--- a/Lib/test/test_io.py
+++ b/Lib/test/test_io.py
@@ -30,6 +30,7 @@
 import signal
 import errno
 import warnings
+import pickle
 from itertools import cycle, count
 from collections import deque
 from test import support
@@ -2566,6 +2567,23 @@
         self._check_warn_on_dealloc_fd("r")
 
 
+    def test_pickling(self):
+        # Pickling file objects is forbidden
+        for kwargs in [
+                {"mode": "w"},
+                {"mode": "wb"},
+                {"mode": "wb", "buffering": 0},
+                {"mode": "r"},
+                {"mode": "rb"},
+                {"mode": "rb", "buffering": 0},
+                {"mode": "w+"},
+                {"mode": "w+b"},
+                {"mode": "w+b", "buffering": 0},
+            ]:
+            for protocol in range(pickle.HIGHEST_PROTOCOL + 1):
+                with self.open(support.TESTFN, **kwargs) as f:
+                    self.assertRaises(TypeError, pickle.dumps, f, protocol)
+
 class CMiscIOTest(MiscIOTest):
     io = io
 
diff --git a/Misc/NEWS b/Misc/NEWS
index af33d28..18c1cde 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -65,6 +65,9 @@
 Library
 -------
 
+- Issue #10180: Pickling file objects is now explicitly forbidden, since
+  unpickling them produced nonsensical results.
+
 - Issue #10311: The signal module now restores errno before returning from
   its low-level signal handler.  Patch by Hallvard B Furuseth.
 
diff --git a/Modules/_io/bufferedio.c b/Modules/_io/bufferedio.c
index 3045169..504e2cb 100644
--- a/Modules/_io/bufferedio.c
+++ b/Modules/_io/bufferedio.c
@@ -549,6 +549,15 @@
     return PyObject_CallMethodObjArgs(self->raw, _PyIO_str_isatty, NULL);
 }
 
+/* Serialization */
+
+static PyObject *
+buffered_getstate(buffered *self, PyObject *args)
+{
+    PyErr_Format(PyExc_TypeError,
+                 "cannot serialize '%s' object", Py_TYPE(self)->tp_name);
+    return NULL;
+}
 
 /* Forward decls */
 static PyObject *
@@ -1489,6 +1498,7 @@
     {"fileno", (PyCFunction)buffered_fileno, METH_NOARGS},
     {"isatty", (PyCFunction)buffered_isatty, METH_NOARGS},
     {"_dealloc_warn", (PyCFunction)buffered_dealloc_warn, METH_O},
+    {"__getstate__", (PyCFunction)buffered_getstate, METH_NOARGS},
 
     {"read", (PyCFunction)buffered_read, METH_VARARGS},
     {"peek", (PyCFunction)buffered_peek, METH_VARARGS},
@@ -1872,6 +1882,7 @@
     {"fileno", (PyCFunction)buffered_fileno, METH_NOARGS},
     {"isatty", (PyCFunction)buffered_isatty, METH_NOARGS},
     {"_dealloc_warn", (PyCFunction)buffered_dealloc_warn, METH_O},
+    {"__getstate__", (PyCFunction)buffered_getstate, METH_NOARGS},
 
     {"write", (PyCFunction)bufferedwriter_write, METH_VARARGS},
     {"truncate", (PyCFunction)buffered_truncate, METH_VARARGS},
@@ -2137,6 +2148,8 @@
     {"close", (PyCFunction)bufferedrwpair_close, METH_NOARGS},
     {"isatty", (PyCFunction)bufferedrwpair_isatty, METH_NOARGS},
 
+    {"__getstate__", (PyCFunction)buffered_getstate, METH_NOARGS},
+
     {NULL, NULL}
 };
 
@@ -2257,6 +2270,7 @@
     {"fileno", (PyCFunction)buffered_fileno, METH_NOARGS},
     {"isatty", (PyCFunction)buffered_isatty, METH_NOARGS},
     {"_dealloc_warn", (PyCFunction)buffered_dealloc_warn, METH_O},
+    {"__getstate__", (PyCFunction)buffered_getstate, METH_NOARGS},
 
     {"flush", (PyCFunction)buffered_flush, METH_NOARGS},
 
diff --git a/Modules/_io/fileio.c b/Modules/_io/fileio.c
index 09ea80f..96fce15 100644
--- a/Modules/_io/fileio.c
+++ b/Modules/_io/fileio.c
@@ -952,6 +952,14 @@
     return PyBool_FromLong(res);
 }
 
+static PyObject *
+fileio_getstate(fileio *self)
+{
+    PyErr_Format(PyExc_TypeError,
+                 "cannot serialize '%s' object", Py_TYPE(self)->tp_name);
+    return NULL;
+}
+
 
 PyDoc_STRVAR(fileio_doc,
 "file(name: str[, mode: str]) -> file IO object\n"
@@ -1046,6 +1054,7 @@
     {"fileno",   (PyCFunction)fileio_fileno,   METH_NOARGS,      fileno_doc},
     {"isatty",   (PyCFunction)fileio_isatty,   METH_NOARGS,      isatty_doc},
     {"_dealloc_warn", (PyCFunction)fileio_dealloc_warn, METH_O, NULL},
+    {"__getstate__", (PyCFunction)fileio_getstate, METH_NOARGS, NULL},
     {NULL,           NULL}             /* sentinel */
 };
 
diff --git a/Modules/_io/textio.c b/Modules/_io/textio.c
index e222067..2559714 100644
--- a/Modules/_io/textio.c
+++ b/Modules/_io/textio.c
@@ -2383,6 +2383,14 @@
 }
 
 static PyObject *
+textiowrapper_getstate(textio *self, PyObject *args)
+{
+    PyErr_Format(PyExc_TypeError,
+                 "cannot serialize '%s' object", Py_TYPE(self)->tp_name);
+    return NULL;
+}
+
+static PyObject *
 textiowrapper_flush(textio *self, PyObject *args)
 {
     CHECK_INITIALIZED(self);
@@ -2546,6 +2554,7 @@
     {"readable", (PyCFunction)textiowrapper_readable, METH_NOARGS},
     {"writable", (PyCFunction)textiowrapper_writable, METH_NOARGS},
     {"isatty", (PyCFunction)textiowrapper_isatty, METH_NOARGS},
+    {"__getstate__", (PyCFunction)textiowrapper_getstate, METH_NOARGS},
 
     {"seek", (PyCFunction)textiowrapper_seek, METH_VARARGS},
     {"tell", (PyCFunction)textiowrapper_tell, METH_NOARGS},