diff --git a/Tools/msi/msi.py b/Tools/msi/msi.py
index 8a72eb9..f06944f 100644
--- a/Tools/msi/msi.py
+++ b/Tools/msi/msi.py
@@ -872,6 +872,12 @@
                     version=version, language=lang)
     tmpfiles.append("msvcr71.dll")
 
+    # Check if _ctypes.pyd exists
+    have_ctypes = os.path.exists(srcdir+"/PCBuild/_ctypes.pyd")
+    if not have_ctypes:
+        print "WARNING: _ctypes.pyd not found, ctypes will not be included"
+        extensions.remove("_ctypes.pyd")
+    
     # Add all .py files in Lib, except lib-tk, test
     dirs={}
     pydirs = [(root,"Lib")]
@@ -889,6 +895,8 @@
             # data: Lib/email/test
             # output: Lib/test
             testsuite.set_current()
+        elif not have_ctypes and dir == "ctypes":
+            continue
         else:
             default_feature.set_current()
         lib = PyDirectory(db, cab, parent, dir, dir, "%s|%s" % (parent.make_short(dir), dir))