Issue #26581: Use the first coding cookie on a line, not the last one.
diff --git a/Lib/idlelib/IOBinding.py b/Lib/idlelib/IOBinding.py
index ef40715..1233d80 100644
--- a/Lib/idlelib/IOBinding.py
+++ b/Lib/idlelib/IOBinding.py
@@ -65,7 +65,7 @@
 
 encoding = encoding.lower()
 
-coding_re = re.compile(r'^[ \t\f]*#.*coding[:=][ \t]*([-\w.]+)')
+coding_re = re.compile(r'^[ \t\f]*#.*?coding[:=][ \t]*([-\w.]+)')
 blank_re = re.compile(r'^[ \t\f]*(?:[#\r\n]|$)')
 
 class EncodingMessage(SimpleDialog):
diff --git a/Lib/lib2to3/pgen2/tokenize.py b/Lib/lib2to3/pgen2/tokenize.py
index d64a3e6..8cae873 100644
--- a/Lib/lib2to3/pgen2/tokenize.py
+++ b/Lib/lib2to3/pgen2/tokenize.py
@@ -236,7 +236,7 @@
                 startline = False
             toks_append(tokval)
 
-cookie_re = re.compile(r'^[ \t\f]*#.*coding[:=][ \t]*([-\w.]+)')
+cookie_re = re.compile(r'^[ \t\f]*#.*?coding[:=][ \t]*([-\w.]+)')
 blank_re = re.compile(r'^[ \t\f]*(?:[#\r\n]|$)')
 
 def _get_normal_name(orig_enc):
diff --git a/Misc/NEWS b/Misc/NEWS
index 56e2cad..3f6ae5d 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -10,6 +10,9 @@
 Core and Builtins
 -----------------
 
+- Issue #26581: If coding cookie is specified multiple times on a line in
+  Python source code file, only the first one is taken to account.
+
 - Issue #22836: Ensure exception reports from PyErr_Display() and
   PyErr_WriteUnraisable() are sensible even when formatting them produces
   secondary errors.  This affects the reports produced by
diff --git a/Tools/scripts/findnocoding.py b/Tools/scripts/findnocoding.py
index 70b1a66..79ea7e5 100755
--- a/Tools/scripts/findnocoding.py
+++ b/Tools/scripts/findnocoding.py
@@ -32,7 +32,7 @@
                          "no sophisticated Python source file search will be done.")
 
 
-decl_re = re.compile(r'^[ \t\f]*#.*coding[:=][ \t]*([-\w.]+)')
+decl_re = re.compile(r'^[ \t\f]*#.*?coding[:=][ \t]*([-\w.]+)')
 blank_re = re.compile(r'^[ \t\f]*(?:[#\r\n]|$)')
 
 def get_declaration(line):