diff --git a/Modules/_sqlite/connection.c b/Modules/_sqlite/connection.c
index 6bc495a..64e27cd 100644
--- a/Modules/_sqlite/connection.c
+++ b/Modules/_sqlite/connection.c
@@ -1197,6 +1197,12 @@
         return NULL;
     }
 
+    statement->db = NULL;
+    statement->st = NULL;
+    statement->sql = NULL;
+    statement->in_use = 0;
+    statement->in_weakreflist = NULL;
+
     rc = pysqlite_statement_create(statement, self, sql);
 
     if (rc != SQLITE_OK) {