diff --git a/Lib/distutils/sysconfig.py b/Lib/distutils/sysconfig.py
index 2ba3c4d..c3b1e4e 100644
--- a/Lib/distutils/sysconfig.py
+++ b/Lib/distutils/sysconfig.py
@@ -512,7 +512,7 @@
                 for key in ('LDFLAGS', 'BASECFLAGS'):
                     flags = _config_vars[key]
                     flags = re.sub('-arch\s+\w+\s', ' ', flags)
-                    flags = re.sub('-isysroot [^ \t]* ', ' ', flags)
+                    flags = re.sub('-isysroot [^ \t]*', ' ', flags)
                     _config_vars[key] = flags
 
     if args:
diff --git a/Lib/distutils/unixccompiler.py b/Lib/distutils/unixccompiler.py
index 324819d..6cd14f7 100644
--- a/Lib/distutils/unixccompiler.py
+++ b/Lib/distutils/unixccompiler.py
@@ -78,7 +78,7 @@
         try:
             index = compiler_so.index('-isysroot')
             # Strip this argument and the next one:
-            del compiler_so[index:index+1]
+            del compiler_so[index:index+2]
         except ValueError:
             pass