there's now a setup.py switch for this
diff --git a/Doc/library/sqlite3.rst b/Doc/library/sqlite3.rst
index 3cad148..7367674 100644
--- a/Doc/library/sqlite3.rst
+++ b/Doc/library/sqlite3.rst
@@ -888,4 +888,4 @@
.. [#f1] The sqlite3 module is not built with loadable extension support by
default, because some platforms (notably Mac OS X) have SQLite libraries which
are compiled without this feature. To get loadable extension support, you must
- modify setup.py and and remove the line that sets SQLITE_OMIT_LOAD_EXTENSION.
+ pass --enable-loadable-sqlite-extensions to configure.