diff --git a/Lib/bsddb/__init__.py b/Lib/bsddb/__init__.py
index d3ee773..68f1032 100644
--- a/Lib/bsddb/__init__.py
+++ b/Lib/bsddb/__init__.py
@@ -358,7 +358,7 @@
         #flags = db.DB_CREATE | db.DB_TRUNCATE
         # we used db.DB_TRUNCATE flag for this before but BerkeleyDB
         # 4.2.52 changed to disallowed truncate with txn environments.
-        if os.path.isfile(file):
+        if file is not None and os.path.isfile(file):
             os.unlink(file)
     else:
         raise error, "flags should be one of 'r', 'w', 'c' or 'n'"
diff --git a/Lib/test/test_bsddb.py b/Lib/test/test_bsddb.py
index 1ec4801..7a0c97c 100755
--- a/Lib/test/test_bsddb.py
+++ b/Lib/test/test_bsddb.py
@@ -11,9 +11,10 @@
 from sets import Set
 
 class TestBSDDB(unittest.TestCase):
+    openflag = 'c'
 
     def setUp(self):
-        self.f = self.openmethod[0](self.fname, 'c')
+        self.f = self.openmethod[0](self.fname, self.openflag)
         self.d = dict(q='Guido', w='van', e='Rossum', r='invented', t='Python', y='')
         for k, v in self.d.iteritems():
             self.f[k] = v
@@ -267,6 +268,11 @@
     fname = None
     openmethod = [bsddb.btopen]
 
+class TestBTree_InMemory_Truncate(TestBSDDB):
+    fname = None
+    openflag = 'n'
+    openmethod = [bsddb.btopen]
+
 class TestHashTable(TestBSDDB):
     fname = test_support.TESTFN
     openmethod = [bsddb.hashopen]
@@ -285,6 +291,7 @@
         TestHashTable,
         TestBTree_InMemory,
         TestHashTable_InMemory,
+        TestBTree_InMemory_Truncate,
     )
 
 if __name__ == "__main__":