diff --git a/PCbuild/python.vcxproj b/PCbuild/python.vcxproj
index 807213f..2786ac2 100644
--- a/PCbuild/python.vcxproj
+++ b/PCbuild/python.vcxproj
@@ -83,7 +83,7 @@
   <Import Project="$(VCTargetsPath)\Microsoft.Cpp.targets" />
   <ImportGroup Label="ExtensionTargets">
   </ImportGroup>
-  <Target Name="ValidateUcrtbase" AfterTargets="AfterBuild">
+  <Target Name="ValidateUcrtbase" AfterTargets="AfterBuild" Condition="$(Configuration) != 'PGInstrument'">
     <PropertyGroup>
       <UcrtName>ucrtbase</UcrtName>
       <UcrtName Condition="'$(Configuration)' == 'Debug'">ucrtbased</UcrtName>
@@ -94,6 +94,8 @@
   </Target>
   <Target Name="GeneratePythonBat" AfterTargets="AfterBuild">
     <PropertyGroup>
+      <_PGOPath Condition="$(Configuration) == 'PGInstrument' and $(Platform) == 'Win32'">@set PATH=%PATH%%3B$(VCInstallDir)bin</_PGOPath>
+      <_PGOPath Condition="$(Configuration) == 'PGInstrument' and $(Platform) == 'x64'">@set PATH=%PATH%%3B$(VCInstallDir)bin\amd64</_PGOPath>
       <_Content>@rem This script invokes the most recently built Python with all arguments
 @rem passed through to the interpreter.  This file is generated by the
 @rem build process and any changes *will* be thrown away by the next
@@ -103,6 +105,7 @@
 @echo Running $(Configuration)^|$(Platform) interpreter...
 @setlocal
 @set PYTHONHOME=$(PySourcePath)
+$(_PGOPath)
 @"$(OutDir)python$(PyDebugExt).exe" %*
 </_Content>
       <_ExistingContent Condition="Exists('$(PySourcePath)python.bat')">$([System.IO.File]::ReadAllText('$(PySourcePath)python.bat'))</_ExistingContent>