diff --git a/Lib/tempfile.py b/Lib/tempfile.py
index efcf7a7..7b68212 100644
--- a/Lib/tempfile.py
+++ b/Lib/tempfile.py
@@ -88,6 +88,10 @@ def _infer_return_type(*args):
     for arg in args:
         if arg is None:
             continue
+
+        if isinstance(arg, _os.PathLike):
+            arg = _os.fspath(arg)
+
         if isinstance(arg, bytes):
             if return_type is str:
                 raise TypeError("Can't mix bytes and non-bytes in "
diff --git a/Lib/test/test_tempfile.py b/Lib/test/test_tempfile.py
index 96946a2..2b0ec46 100644
--- a/Lib/test/test_tempfile.py
+++ b/Lib/test/test_tempfile.py
@@ -62,6 +62,25 @@ def test_infer_return_type_multiples_and_none(self):
     def test_infer_return_type_pathlib(self):
         self.assertIs(str, tempfile._infer_return_type(pathlib.Path('/')))
 
+    def test_infer_return_type_pathlike(self):
+        class Path:
+            def __init__(self, path):
+                self.path = path
+
+            def __fspath__(self):
+                return self.path
+
+        self.assertIs(str, tempfile._infer_return_type(Path('/')))
+        self.assertIs(bytes, tempfile._infer_return_type(Path(b'/')))
+        self.assertIs(str, tempfile._infer_return_type('', Path('')))
+        self.assertIs(bytes, tempfile._infer_return_type(b'', Path(b'')))
+        self.assertIs(bytes, tempfile._infer_return_type(None, Path(b'')))
+        self.assertIs(str, tempfile._infer_return_type(None, Path('')))
+
+        with self.assertRaises(TypeError):
+            tempfile._infer_return_type('', Path(b''))
+        with self.assertRaises(TypeError):
+            tempfile._infer_return_type(b'', Path(''))
 
 # Common functionality.
 
diff --git a/Misc/NEWS.d/next/Library/2021-09-14-15-52-47.bpo-45192.DjA-BI.rst b/Misc/NEWS.d/next/Library/2021-09-14-15-52-47.bpo-45192.DjA-BI.rst
new file mode 100644
index 0000000..7dd9795
--- /dev/null
+++ b/Misc/NEWS.d/next/Library/2021-09-14-15-52-47.bpo-45192.DjA-BI.rst
@@ -0,0 +1,5 @@
+Fix the ``tempfile._infer_return_type`` function so that the ``dir``
+argument of the :mod:`tempfile` functions accepts an object implementing the
+``os.PathLike`` protocol.
+
+Patch by Kyungmin Lee.