diff --git a/Misc/NEWS b/Misc/NEWS
index a4d301f..9eaed9a 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -1492,6 +1492,8 @@
 Extension Modules
 -----------------
 
+- Issue #9422: Fix memory leak when re-initializing a struct.Struct object.
+
 - Issue #7900: The getgroups(2) system call on MacOSX behaves rather oddly
   compared to other unix systems. In particular, os.getgroups() does
   not reflect any changes made using os.setgroups() but basicly always
diff --git a/Modules/_struct.c b/Modules/_struct.c
index d55ce0f..f85d562 100644
--- a/Modules/_struct.c
+++ b/Modules/_struct.c
@@ -1247,6 +1247,9 @@
         PyErr_NoMemory();
         return -1;
     }
+    /* Free any s_codes value left over from a previous initialization. */
+    if (self->s_codes != NULL)
+        PyMem_FREE(self->s_codes);
     self->s_codes = codes;
 
     s = fmt;