diff --git a/Doc/library/math.rst b/Doc/library/math.rst
index da2b8cc..42bbb02 100644
--- a/Doc/library/math.rst
+++ b/Doc/library/math.rst
@@ -57,6 +57,21 @@
    If *x* is not a float, delegates to ``x.__floor__()``, which should return an
    :class:`~numbers.Integral` value.
 
+.. function:: fma(x, y, z)
+
+   Fused multiply-add operation. Return ``(x * y) + z``, computed as though with
+   infinite precision and range followed by a single round to the ``float``
+   format. This operation often provides better accuracy than the direct
+   expression ``(x * y) + z``.
+
+   This function follows the specification of the fusedMultiplyAdd operation
+   described in the IEEE 754-2008 standard. The standard leaves one case
+   implementation-defined, namely the result of ``fma(0, inf, nan)``
+   and ``fma(inf, 0, nan)``. In these cases, ``math.fma`` returns a NaN,
+   and does not raise any exception.
+
+   .. versionadded:: 3.7
+
 
 .. function:: fmod(x, y)
 
diff --git a/Doc/whatsnew/3.7.rst b/Doc/whatsnew/3.7.rst
index fe03def..192a7ab 100644
--- a/Doc/whatsnew/3.7.rst
+++ b/Doc/whatsnew/3.7.rst
@@ -100,6 +100,15 @@
 when they are :mod:`copied <copy>` or :mod:`pickled <pickle>`.
 (Contributed by Serhiy Storchaka in :issue:`20804`.)
 
+math module
+-----------
+
+A new function :func:`~math.fma` for fused multiply-add operations has been
+added. This function computes ``x * y + z`` with only a single round, and so
+avoids any intermediate loss of precision. It wraps the ``fma`` function
+provided by C99, and follows the specification of the IEEE 754-2008
+"fusedMultiplyAdd" operation for special cases.
+
 
 Optimizations
 =============
diff --git a/Lib/test/test_math.py b/Lib/test/test_math.py
index eaa41bc..516a004 100644
--- a/Lib/test/test_math.py
+++ b/Lib/test/test_math.py
@@ -4,6 +4,7 @@
 from test.support import run_unittest, verbose, requires_IEEE_754
 from test import support
 import unittest
+import itertools
 import math
 import os
 import platform
@@ -1410,11 +1411,244 @@
         self.assertAllNotClose(fraction_examples, rel_tol=1e-9)
 
 
+class FMATests(unittest.TestCase):
+    """ Tests for math.fma. """
+
+    def test_fma_nan_results(self):
+        # Selected representative values.
+        values = [
+            -math.inf, -1e300, -2.3, -1e-300, -0.0,
+            0.0, 1e-300, 2.3, 1e300, math.inf, math.nan
+        ]
+
+        # If any input is a NaN, the result should be a NaN, too.
+        for a, b in itertools.product(values, repeat=2):
+            self.assertIsNaN(math.fma(math.nan, a, b))
+            self.assertIsNaN(math.fma(a, math.nan, b))
+            self.assertIsNaN(math.fma(a, b, math.nan))
+
+    def test_fma_infinities(self):
+        # Cases involving infinite inputs or results.
+        positives = [1e-300, 2.3, 1e300, math.inf]
+        finites = [-1e300, -2.3, -1e-300, -0.0, 0.0, 1e-300, 2.3, 1e300]
+        non_nans = [-math.inf, -2.3, -0.0, 0.0, 2.3, math.inf]
+
+        # ValueError due to inf * 0 computation.
+        for c in non_nans:
+            for infinity in [math.inf, -math.inf]:
+                for zero in [0.0, -0.0]:
+                    with self.assertRaises(ValueError):
+                        math.fma(infinity, zero, c)
+                    with self.assertRaises(ValueError):
+                        math.fma(zero, infinity, c)
+
+        # ValueError when a*b and c both infinite of opposite signs.
+        for b in positives:
+            with self.assertRaises(ValueError):
+                math.fma(math.inf, b, -math.inf)
+            with self.assertRaises(ValueError):
+                math.fma(math.inf, -b, math.inf)
+            with self.assertRaises(ValueError):
+                math.fma(-math.inf, -b, -math.inf)
+            with self.assertRaises(ValueError):
+                math.fma(-math.inf, b, math.inf)
+            with self.assertRaises(ValueError):
+                math.fma(b, math.inf, -math.inf)
+            with self.assertRaises(ValueError):
+                math.fma(-b, math.inf, math.inf)
+            with self.assertRaises(ValueError):
+                math.fma(-b, -math.inf, -math.inf)
+            with self.assertRaises(ValueError):
+                math.fma(b, -math.inf, math.inf)
+
+        # Infinite result when a*b and c both infinite of the same sign.
+        for b in positives:
+            self.assertEqual(math.fma(math.inf, b, math.inf), math.inf)
+            self.assertEqual(math.fma(math.inf, -b, -math.inf), -math.inf)
+            self.assertEqual(math.fma(-math.inf, -b, math.inf), math.inf)
+            self.assertEqual(math.fma(-math.inf, b, -math.inf), -math.inf)
+            self.assertEqual(math.fma(b, math.inf, math.inf), math.inf)
+            self.assertEqual(math.fma(-b, math.inf, -math.inf), -math.inf)
+            self.assertEqual(math.fma(-b, -math.inf, math.inf), math.inf)
+            self.assertEqual(math.fma(b, -math.inf, -math.inf), -math.inf)
+
+        # Infinite result when a*b finite, c infinite.
+        for a, b in itertools.product(finites, finites):
+            self.assertEqual(math.fma(a, b, math.inf), math.inf)
+            self.assertEqual(math.fma(a, b, -math.inf), -math.inf)
+
+        # Infinite result when a*b infinite, c finite.
+        for b, c in itertools.product(positives, finites):
+            self.assertEqual(math.fma(math.inf, b, c), math.inf)
+            self.assertEqual(math.fma(-math.inf, b, c), -math.inf)
+            self.assertEqual(math.fma(-math.inf, -b, c), math.inf)
+            self.assertEqual(math.fma(math.inf, -b, c), -math.inf)
+
+            self.assertEqual(math.fma(b, math.inf, c), math.inf)
+            self.assertEqual(math.fma(b, -math.inf, c), -math.inf)
+            self.assertEqual(math.fma(-b, -math.inf, c), math.inf)
+            self.assertEqual(math.fma(-b, math.inf, c), -math.inf)
+
+    def test_fma_zero_result(self):
+        nonnegative_finites = [0.0, 1e-300, 2.3, 1e300]
+
+        # Zero results from exact zero inputs.
+        for b in nonnegative_finites:
+            self.assertIsPositiveZero(math.fma(0.0, b, 0.0))
+            self.assertIsPositiveZero(math.fma(0.0, b, -0.0))
+            self.assertIsNegativeZero(math.fma(0.0, -b, -0.0))
+            self.assertIsPositiveZero(math.fma(0.0, -b, 0.0))
+            self.assertIsPositiveZero(math.fma(-0.0, -b, 0.0))
+            self.assertIsPositiveZero(math.fma(-0.0, -b, -0.0))
+            self.assertIsNegativeZero(math.fma(-0.0, b, -0.0))
+            self.assertIsPositiveZero(math.fma(-0.0, b, 0.0))
+
+            self.assertIsPositiveZero(math.fma(b, 0.0, 0.0))
+            self.assertIsPositiveZero(math.fma(b, 0.0, -0.0))
+            self.assertIsNegativeZero(math.fma(-b, 0.0, -0.0))
+            self.assertIsPositiveZero(math.fma(-b, 0.0, 0.0))
+            self.assertIsPositiveZero(math.fma(-b, -0.0, 0.0))
+            self.assertIsPositiveZero(math.fma(-b, -0.0, -0.0))
+            self.assertIsNegativeZero(math.fma(b, -0.0, -0.0))
+            self.assertIsPositiveZero(math.fma(b, -0.0, 0.0))
+
+        # Exact zero result from nonzero inputs.
+        self.assertIsPositiveZero(math.fma(2.0, 2.0, -4.0))
+        self.assertIsPositiveZero(math.fma(2.0, -2.0, 4.0))
+        self.assertIsPositiveZero(math.fma(-2.0, -2.0, -4.0))
+        self.assertIsPositiveZero(math.fma(-2.0, 2.0, 4.0))
+
+        # Underflow to zero.
+        tiny = 1e-300
+        self.assertIsPositiveZero(math.fma(tiny, tiny, 0.0))
+        self.assertIsNegativeZero(math.fma(tiny, -tiny, 0.0))
+        self.assertIsPositiveZero(math.fma(-tiny, -tiny, 0.0))
+        self.assertIsNegativeZero(math.fma(-tiny, tiny, 0.0))
+        self.assertIsPositiveZero(math.fma(tiny, tiny, -0.0))
+        self.assertIsNegativeZero(math.fma(tiny, -tiny, -0.0))
+        self.assertIsPositiveZero(math.fma(-tiny, -tiny, -0.0))
+        self.assertIsNegativeZero(math.fma(-tiny, tiny, -0.0))
+
+        # Corner case where rounding the multiplication would
+        # give the wrong result.
+        x = float.fromhex('0x1p-500')
+        y = float.fromhex('0x1p-550')
+        z = float.fromhex('0x1p-1000')
+        self.assertIsNegativeZero(math.fma(x-y, x+y, -z))
+        self.assertIsPositiveZero(math.fma(y-x, x+y, z))
+        self.assertIsNegativeZero(math.fma(y-x, -(x+y), -z))
+        self.assertIsPositiveZero(math.fma(x-y, -(x+y), z))
+
+    def test_fma_overflow(self):
+        a = b = float.fromhex('0x1p512')
+        c = float.fromhex('0x1p1023')
+        # Overflow from multiplication.
+        with self.assertRaises(OverflowError):
+            math.fma(a, b, 0.0)
+        self.assertEqual(math.fma(a, b/2.0, 0.0), c)
+        # Overflow from the addition.
+        with self.assertRaises(OverflowError):
+            math.fma(a, b/2.0, c)
+        # No overflow, even though a*b overflows a float.
+        self.assertEqual(math.fma(a, b, -c), c)
+
+        # Extreme case: a * b is exactly at the overflow boundary, so the
+        # tiniest offset makes a difference between overflow and a finite
+        # result.
+        a = float.fromhex('0x1.ffffffc000000p+511')
+        b = float.fromhex('0x1.0000002000000p+512')
+        c = float.fromhex('0x0.0000000000001p-1022')
+        with self.assertRaises(OverflowError):
+            math.fma(a, b, 0.0)
+        with self.assertRaises(OverflowError):
+            math.fma(a, b, c)
+        self.assertEqual(math.fma(a, b, -c),
+                         float.fromhex('0x1.fffffffffffffp+1023'))
+
+        # Another extreme case: here a*b is about as large as possible subject
+        # to math.fma(a, b, c) being finite.
+        a = float.fromhex('0x1.ae565943785f9p+512')
+        b = float.fromhex('0x1.3094665de9db8p+512')
+        c = float.fromhex('0x1.fffffffffffffp+1023')
+        self.assertEqual(math.fma(a, b, -c), c)
+
+    def test_fma_single_round(self):
+        a = float.fromhex('0x1p-50')
+        self.assertEqual(math.fma(a - 1.0, a + 1.0, 1.0), a*a)
+
+    def test_random(self):
+        # A collection of randomly generated inputs for which the naive FMA
+        # (with two rounds) gives a different result from a singly-rounded FMA.
+
+        # tuples (a, b, c, expected)
+        test_values = [
+            ('0x1.694adde428b44p-1', '0x1.371b0d64caed7p-1',
+             '0x1.f347e7b8deab8p-4', '0x1.19f10da56c8adp-1'),
+            ('0x1.605401ccc6ad6p-2', '0x1.ce3a40bf56640p-2',
+             '0x1.96e3bf7bf2e20p-2', '0x1.1af6d8aa83101p-1'),
+            ('0x1.e5abd653a67d4p-2', '0x1.a2e400209b3e6p-1',
+             '0x1.a90051422ce13p-1', '0x1.37d68cc8c0fbbp+0'),
+            ('0x1.f94e8efd54700p-2', '0x1.123065c812cebp-1',
+             '0x1.458f86fb6ccd0p-1', '0x1.ccdcee26a3ff3p-1'),
+            ('0x1.bd926f1eedc96p-1', '0x1.eee9ca68c5740p-1',
+             '0x1.960c703eb3298p-2', '0x1.3cdcfb4fdb007p+0'),
+            ('0x1.27348350fbccdp-1', '0x1.3b073914a53f1p-1',
+             '0x1.e300da5c2b4cbp-1', '0x1.4c51e9a3c4e29p+0'),
+            ('0x1.2774f00b3497bp-1', '0x1.7038ec336bff0p-2',
+             '0x1.2f6f2ccc3576bp-1', '0x1.99ad9f9c2688bp-1'),
+            ('0x1.51d5a99300e5cp-1', '0x1.5cd74abd445a1p-1',
+             '0x1.8880ab0bbe530p-1', '0x1.3756f96b91129p+0'),
+            ('0x1.73cb965b821b8p-2', '0x1.218fd3d8d5371p-1',
+             '0x1.d1ea966a1f758p-2', '0x1.5217b8fd90119p-1'),
+            ('0x1.4aa98e890b046p-1', '0x1.954d85dff1041p-1',
+             '0x1.122b59317ebdfp-1', '0x1.0bf644b340cc5p+0'),
+            ('0x1.e28f29e44750fp-1', '0x1.4bcc4fdcd18fep-1',
+             '0x1.fd47f81298259p-1', '0x1.9b000afbc9995p+0'),
+            ('0x1.d2e850717fe78p-3', '0x1.1dd7531c303afp-1',
+             '0x1.e0869746a2fc2p-2', '0x1.316df6eb26439p-1'),
+            ('0x1.cf89c75ee6fbap-2', '0x1.b23decdc66825p-1',
+             '0x1.3d1fe76ac6168p-1', '0x1.00d8ea4c12abbp+0'),
+            ('0x1.3265ae6f05572p-2', '0x1.16d7ec285f7a2p-1',
+             '0x1.0b8405b3827fbp-1', '0x1.5ef33c118a001p-1'),
+            ('0x1.c4d1bf55ec1a5p-1', '0x1.bc59618459e12p-2',
+             '0x1.ce5b73dc1773dp-1', '0x1.496cf6164f99bp+0'),
+            ('0x1.d350026ac3946p-1', '0x1.9a234e149a68cp-2',
+             '0x1.f5467b1911fd6p-2', '0x1.b5cee3225caa5p-1'),
+        ]
+        for a_hex, b_hex, c_hex, expected_hex in test_values:
+            a = float.fromhex(a_hex)
+            b = float.fromhex(b_hex)
+            c = float.fromhex(c_hex)
+            expected = float.fromhex(expected_hex)
+            self.assertEqual(math.fma(a, b, c), expected)
+            self.assertEqual(math.fma(b, a, c), expected)
+
+    # Custom assertions.
+    def assertIsNaN(self, value):
+        self.assertTrue(
+            math.isnan(value),
+            msg="Expected a NaN, got {!r}".format(value)
+        )
+
+    def assertIsPositiveZero(self, value):
+        self.assertTrue(
+            value == 0 and math.copysign(1, value) > 0,
+            msg="Expected a positive zero, got {!r}".format(value)
+        )
+
+    def assertIsNegativeZero(self, value):
+        self.assertTrue(
+            value == 0 and math.copysign(1, value) < 0,
+            msg="Expected a negative zero, got {!r}".format(value)
+        )
+
+
 def test_main():
     from doctest import DocFileSuite
     suite = unittest.TestSuite()
     suite.addTest(unittest.makeSuite(MathTests))
     suite.addTest(unittest.makeSuite(IsCloseTests))
+    suite.addTest(unittest.makeSuite(FMATests))
     suite.addTest(DocFileSuite("ieee754.txt"))
     run_unittest(suite)
 
diff --git a/Misc/NEWS b/Misc/NEWS
index cb2ac85..dd6169a 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -215,6 +215,9 @@
 Library
 -------
 
+- Issue #29282: Added new math.fma function, wrapping C99's fma
+  operation.
+
 - Issue #29197: Removed deprecated function ntpath.splitunc().
 
 - Issue #29210: Removed support of deprecated argument "exclude" in
diff --git a/Modules/clinic/mathmodule.c.h b/Modules/clinic/mathmodule.c.h
index 84a7a70..4e9fe20 100644
--- a/Modules/clinic/mathmodule.c.h
+++ b/Modules/clinic/mathmodule.c.h
@@ -80,6 +80,40 @@
 #define MATH_FACTORIAL_METHODDEF    \
     {"factorial", (PyCFunction)math_factorial, METH_O, math_factorial__doc__},
 
+PyDoc_STRVAR(math_fma__doc__,
+"fma($module, x, y, z, /)\n"
+"--\n"
+"\n"
+"Fused multiply-add operation. Compute (x * y) + z with a single round.");
+
+#define MATH_FMA_METHODDEF    \
+    {"fma", (PyCFunction)math_fma, METH_FASTCALL, math_fma__doc__},
+
+static PyObject *
+math_fma_impl(PyObject *module, double x, double y, double z);
+
+static PyObject *
+math_fma(PyObject *module, PyObject **args, Py_ssize_t nargs, PyObject *kwnames)
+{
+    PyObject *return_value = NULL;
+    double x;
+    double y;
+    double z;
+
+    if (!_PyArg_ParseStack(args, nargs, "ddd:fma",
+        &x, &y, &z)) {
+        goto exit;
+    }
+
+    if (!_PyArg_NoStackKeywords("fma", kwnames)) {
+        goto exit;
+    }
+    return_value = math_fma_impl(module, x, y, z);
+
+exit:
+    return return_value;
+}
+
 PyDoc_STRVAR(math_trunc__doc__,
 "trunc($module, x, /)\n"
 "--\n"
@@ -536,4 +570,4 @@
 exit:
     return return_value;
 }
-/*[clinic end generated code: output=71806f73a5c4bf0b input=a9049054013a1b77]*/
+/*[clinic end generated code: output=f428e1075d00c334 input=a9049054013a1b77]*/
diff --git a/Modules/mathmodule.c b/Modules/mathmodule.c
index 8bd38d0..66e88b6 100644
--- a/Modules/mathmodule.c
+++ b/Modules/mathmodule.c
@@ -1596,6 +1596,47 @@
 
 
 /*[clinic input]
+math.fma
+
+    x: double
+    y: double
+    z: double
+    /
+
+Fused multiply-add operation. Compute (x * y) + z with a single round.
+[clinic start generated code]*/
+
+static PyObject *
+math_fma_impl(PyObject *module, double x, double y, double z)
+/*[clinic end generated code: output=4fc8626dbc278d17 input=2ae8bb2a6e0f8b77]*/
+{
+    double r;
+    r = fma(x, y, z);
+
+    /* Fast path: if we got a finite result, we're done. */
+    if (Py_IS_FINITE(r)) {
+        return PyFloat_FromDouble(r);
+    }
+
+    /* Non-finite result. Raise an exception if appropriate, else return r. */
+    if (Py_IS_NAN(r)) {
+        if (!Py_IS_NAN(x) && !Py_IS_NAN(y) && !Py_IS_NAN(z)) {
+            /* NaN result from non-NaN inputs. */
+            PyErr_SetString(PyExc_ValueError, "invalid operation in fma");
+            return NULL;
+        }
+    }
+    else if (Py_IS_FINITE(x) && Py_IS_FINITE(y) && Py_IS_FINITE(z)) {
+        /* Infinite result from finite inputs. */
+        PyErr_SetString(PyExc_OverflowError, "overflow in fma");
+        return NULL;
+    }
+
+    return PyFloat_FromDouble(r);
+}
+
+
+/*[clinic input]
 math.trunc
 
     x: object
@@ -2224,6 +2265,7 @@
     {"fabs",            math_fabs,      METH_O,         math_fabs_doc},
     MATH_FACTORIAL_METHODDEF
     MATH_FLOOR_METHODDEF
+    MATH_FMA_METHODDEF
     MATH_FMOD_METHODDEF
     MATH_FREXP_METHODDEF
     MATH_FSUM_METHODDEF