diff --git a/Misc/NEWS.d/next/Build/2021-10-11-16-27-38.bpo-45405.iSfdW5.rst b/Misc/NEWS.d/next/Build/2021-10-11-16-27-38.bpo-45405.iSfdW5.rst
new file mode 100644
index 0000000..a2dc5bc
--- /dev/null
+++ b/Misc/NEWS.d/next/Build/2021-10-11-16-27-38.bpo-45405.iSfdW5.rst
@@ -0,0 +1,2 @@
+Prevent ``internal configure error`` when running ``configure``
+with recent versions of non-Apple clang.  Patch by David Bohman.
diff --git a/configure b/configure
index 02d882e..a6e0f82 100755
--- a/configure
+++ b/configure
@@ -5226,9 +5226,6 @@
 fi
 
 
-MULTIARCH=$($CC --print-multiarch 2>/dev/null)
-
-
 { $as_echo "$as_me:${as_lineno-$LINENO}: checking for the platform triplet based on compiler characteristics" >&5
 $as_echo_n "checking for the platform triplet based on compiler characteristics... " >&6; }
 cat >> conftest.c <<EOF
@@ -5387,6 +5384,11 @@
 fi
 rm -f conftest.c conftest.out
 
+if test x$PLATFORM_TRIPLET != xdarwin; then
+  MULTIARCH=$($CC --print-multiarch 2>/dev/null)
+fi
+
+
 if test x$PLATFORM_TRIPLET != x && test x$MULTIARCH != x; then
   if test x$PLATFORM_TRIPLET != x$MULTIARCH; then
     as_fn_error $? "internal configure error for the platform triplet, please file a bug report" "$LINENO" 5
diff --git a/configure.ac b/configure.ac
index 41a3679..c4abac6 100644
--- a/configure.ac
+++ b/configure.ac
@@ -717,9 +717,6 @@
 fi
 
 
-MULTIARCH=$($CC --print-multiarch 2>/dev/null)
-AC_SUBST(MULTIARCH)
-
 AC_MSG_CHECKING([for the platform triplet based on compiler characteristics])
 cat >> conftest.c <<EOF
 #undef bfin
@@ -875,6 +872,11 @@
 fi
 rm -f conftest.c conftest.out
 
+if test x$PLATFORM_TRIPLET != xdarwin; then
+  MULTIARCH=$($CC --print-multiarch 2>/dev/null)
+fi
+AC_SUBST(MULTIARCH)
+
 if test x$PLATFORM_TRIPLET != x && test x$MULTIARCH != x; then
   if test x$PLATFORM_TRIPLET != x$MULTIARCH; then
     AC_MSG_ERROR([internal configure error for the platform triplet, please file a bug report])