diff --git a/googleapiclient/discovery.py b/googleapiclient/discovery.py
index 1b7aedd..1004f30 100644
--- a/googleapiclient/discovery.py
+++ b/googleapiclient/discovery.py
@@ -44,6 +44,7 @@
 import google.api_core.client_options
 from google.auth.transport import mtls
 from google.auth.exceptions import MutualTLSChannelError
+from google.oauth2 import service_account
 
 try:
     import google_auth_httplib2
@@ -188,6 +189,7 @@
     adc_key_path=None,
     num_retries=1,
     static_discovery=None,
+    always_use_jwt_access=True,
 ):
     """Construct a Resource for interacting with an API.
 
@@ -246,6 +248,9 @@
       on the value of `discoveryServiceUrl`. `static_discovery` will default to
       `True` when `discoveryServiceUrl` is also not provided, otherwise it will
       default to `False`.
+    always_use_jwt_access: Boolean, whether always use self signed JWT for service
+      account credentials. This only applies to
+      google.oauth2.service_account.Credentials.
 
   Returns:
     A Resource object with methods for interacting with the service.
@@ -301,6 +306,7 @@
                 client_options=client_options,
                 adc_cert_path=adc_cert_path,
                 adc_key_path=adc_key_path,
+                always_use_jwt_access=always_use_jwt_access,
             )
             break  # exit if a service was created
         except HttpError as e:
@@ -441,6 +447,7 @@
     client_options=None,
     adc_cert_path=None,
     adc_key_path=None,
+    always_use_jwt_access=True,
 ):
     """Create a Resource for interacting with an API.
 
@@ -490,6 +497,9 @@
       `true` in order to use this field, otherwise this field doesn't nothing.
       More details on the environment variables are here:
       https://google.aip.dev/auth/4114
+    always_use_jwt_access: Boolean, whether always use self signed JWT for service
+      account credentials. This only applies to
+      google.oauth2.service_account.Credentials.
 
   Returns:
     A Resource object with methods for interacting with the service.
@@ -530,6 +540,7 @@
 
     # If an API Endpoint is provided on client options, use that as the base URL
     base = urllib.parse.urljoin(service["rootUrl"], service["servicePath"])
+    audience_for_self_signed_jwt = base
     if client_options.api_endpoint:
         base = client_options.api_endpoint
 
@@ -572,6 +583,17 @@
             if not client_options.scopes:
                 credentials = _auth.with_scopes(credentials, scopes)
 
+        # For google-auth service account credentials, enable self signed JWT if
+        # always_use_jwt_access is true.
+        if (
+            credentials
+            and isinstance(credentials, service_account.Credentials)
+            and always_use_jwt_access
+            and hasattr(service_account.Credentials, "with_always_use_jwt_access")
+        ):
+            credentials = credentials.with_always_use_jwt_access(always_use_jwt_access)
+            credentials._create_self_signed_jwt(audience_for_self_signed_jwt)
+
         # If credentials are provided, create an authorized http instance;
         # otherwise, skip authentication.
         if credentials:
diff --git a/tests/data/service_account.json b/tests/data/service_account.json
new file mode 100644
index 0000000..b711fee
--- /dev/null
+++ b/tests/data/service_account.json
@@ -0,0 +1,10 @@
+{
+    "type": "service_account",
+    "project_id": "example-project",
+    "private_key_id": "1",
+    "private_key": "-----BEGIN RSA PRIVATE KEY-----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\nBeF5CT/JuNYk3bEBF0H/Q3VGO1/ggVS+YezdFbLWIRoMnLj6XCFEGg==\n-----END RSA PRIVATE KEY-----\n",
+    "client_email": "service-account@example.com",
+    "client_id": "1234",
+    "auth_uri": "https://accounts.google.com/o/oauth2/auth",
+    "token_uri": "https://accounts.google.com/o/oauth2/token"
+  }
\ No newline at end of file
diff --git a/tests/test_discovery.py b/tests/test_discovery.py
index 9500fbf..2f3f028 100644
--- a/tests/test_discovery.py
+++ b/tests/test_discovery.py
@@ -685,6 +685,33 @@
             "credentials.json", scopes=None, quota_project_id=None
         )
 
+    def test_self_signed_jwt_enabled(self):
+        service_account_file_path = os.path.join(DATA_DIR, "service_account.json")
+        creds = google.oauth2.service_account.Credentials.from_service_account_file(service_account_file_path)
+
+        discovery = read_datafile("logging.json")
+
+        with mock.patch("google.oauth2.service_account.Credentials._create_self_signed_jwt") as _create_self_signed_jwt:
+            build_from_document(
+                discovery,
+                credentials=creds,
+            )
+            _create_self_signed_jwt.assert_called_with("https://logging.googleapis.com/")
+
+    def test_self_signed_jwt_disabled(self):
+        service_account_file_path = os.path.join(DATA_DIR, "service_account.json")
+        creds = google.oauth2.service_account.Credentials.from_service_account_file(service_account_file_path)
+
+        discovery = read_datafile("logging.json")
+
+        with mock.patch("google.oauth2.service_account.Credentials._create_self_signed_jwt") as _create_self_signed_jwt:
+            build_from_document(
+                discovery,
+                credentials=creds,
+                always_use_jwt_access=False,
+            )
+            _create_self_signed_jwt.assert_not_called()
+
 
 REGULAR_ENDPOINT = "https://www.googleapis.com/plus/v1/"
 MTLS_ENDPOINT = "https://www.mtls.googleapis.com/plus/v1/"