diff --git a/CMakeLists.txt b/CMakeLists.txt
index 4440b90..1a344bd 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -148,17 +148,19 @@
 
 if (WIN32)
   if (MSVC)
-    # /bigobj is needed for bigger binding projects due to the limit to 64k
-    # addressable sections. /MP enables multithreaded builds (relevant when
-    # there are many files).
-    set_target_properties(example PROPERTIES COMPILE_FLAGS "/MP /bigobj ")
-
-    if (NOT ${U_CMAKE_BUILD_TYPE} MATCHES DEBUG)
-      # Enforce size-based optimization and link time code generation on MSVC
-      # (~30% smaller binaries in experiments).
-      set_target_properties(example APPEND_STRING PROPERTY COMPILE_FLAGS "/Os /GL ")
-      set_target_properties(example APPEND_STRING PROPERTY LINK_FLAGS "/LTCG ")
-    endif()
+    # /MP enables multithreaded builds (relevant when there are many files), /bigobj is
+    # needed for bigger binding projects due to the limit to 64k addressable sections
+    set_property(TARGET example APPEND PROPERTY COMPILE_OPTIONS /MP /bigobj)
+    # Enforce size-based optimization and link time code generation on MSVC
+    # (~30% smaller binaries in experiments); do nothing in debug mode.
+    set_property(TARGET example APPEND PROPERTY COMPILE_OPTIONS
+      "$<$<CONFIG:Release>:/Os>" "$<$<CONFIG:Release>:/GL>"
+      "$<$<CONFIG:MinSizeRel>:/Os>" "$<$<CONFIG:MinSizeRel>:/GL>"
+      "$<$<CONFIG:RelWithDebInfo>:/Os>" "$<$<CONFIG:RelWithDebInfo>:/GL>"
+    )
+    set_property(TARGET example APPEND_STRING PROPERTY LINK_FLAGS_RELEASE "/LTCG ")
+    set_property(TARGET example APPEND_STRING PROPERTY LINK_FLAGS_MINSIZEREL "/LTCG ")
+    set_property(TARGET example APPEND_STRING PROPERTY LINK_FLAGS_RELWITHDEBINFO "/LTCG ")
   endif()
 
   # .PYD file extension on Windows
diff --git a/docs/cmake.rst b/docs/cmake.rst
index 7236ea8..0298303 100644
--- a/docs/cmake.rst
+++ b/docs/cmake.rst
@@ -106,17 +106,19 @@
 
     if (WIN32)
       if (MSVC)
-        # /bigobj is needed for bigger binding projects due to the limit to 64k
-        # addressable sections. /MP enables multithreaded builds (relevant when
-        # there are many files).
-        set_target_properties(example PROPERTIES COMPILE_FLAGS "/MP /bigobj ")
-
-        if (NOT ${U_CMAKE_BUILD_TYPE} MATCHES DEBUG)
-          # Enforce size-based optimization and link time code generation on MSVC
-          # (~30% smaller binaries in experiments).
-          set_target_properties(example APPEND_STRING PROPERTY COMPILE_FLAGS "/Os /GL ")
-          set_target_properties(example APPEND_STRING PROPERTY LINK_FLAGS "/LTCG ")
-        endif()
+        # /MP enables multithreaded builds (relevant when there are many files), /bigobj is
+        # needed for bigger binding projects due to the limit to 64k addressable sections
+        set_property(TARGET example APPEND PROPERTY COMPILE_OPTIONS /MP /bigobj)
+        # Enforce size-based optimization and link time code generation on MSVC
+        # (~30% smaller binaries in experiments); do nothing in debug mode.
+        set_property(TARGET example APPEND PROPERTY COMPILE_OPTIONS
+          "$<$<CONFIG:Release>:/Os>" "$<$<CONFIG:Release>:/GL>"
+          "$<$<CONFIG:MinSizeRel>:/Os>" "$<$<CONFIG:MinSizeRel>:/GL>"
+          "$<$<CONFIG:RelWithDebInfo>:/Os>" "$<$<CONFIG:RelWithDebInfo>:/GL>"
+        )
+        set_property(TARGET example APPEND_STRING PROPERTY LINK_FLAGS_RELEASE "/LTCG ")
+        set_property(TARGET example APPEND_STRING PROPERTY LINK_FLAGS_MINSIZEREL "/LTCG ")
+        set_property(TARGET example APPEND_STRING PROPERTY LINK_FLAGS_RELWITHDEBINFO "/LTCG ")
       endif()
 
       # .PYD file extension on Windows